Breaking news on breaking bones: Bone remodelling and type 1 osteoporosis

This animation introduces the concepts of bone remodelling and type 1 osteoporosis. The animation will first guide the audience through a basic overview of bone remodeling using the metaphor of a construction site. Furthermore, the animation will discuss the role of estrogen in type 1 osteoporosis and, finally, conclude with preventative measures.

Topics

• Explain why calcium is needed in blood plasma
• Define homeostasis and feedback loops
• Identify the main hormones involved in regulating blood-calcium levels; thyroid and parathyroid hormone
• Explain the cause and effect of thyroid and parathyroid hormone release
• Clarify the multiple roles of vitamin D in balancing blood-calcium levels
• Review the effects of calcium metabolism on osteoblast and osteoclast activity

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