Sarah Lessard, Ph.D., is an Assistant Investigator in the section of Clinical, Behavioral and Outcomes Research at the Joslin Diabetes Center, which is one of the world's leading institutions dedicated to diabetes research and care. She also holds a joint appointment as Assistant Professor of Medicine at Harvard Medical School. The focus of the Lessard laboratory is to determine the molecular mechanisms behind the powerful clinical benefits of exercise, and uncover the specific contributions of skeletal muscle to health and disease. Dr. Lessard is also a member of the NIH Molecular Transducers of Physical Activity Consortium (MoTrPAC), which aims to define the molecular map of signals that transmit the health effects of physical activity.
- Highlight low aerobic exercise capacity as an important clinical risk factor for chronic disease and mortality.
- Understand how metabolic disease may impact the health benefits of aerobic exercise training by inhibiting improvements in exercise capacity.
- Identify molecular mechanisms that may underlie blunted response to exercise in individuals with metabolic disease.