Publication of the Week 

March 18, 2022Keith A A Fox, Saverio Virdone, Karen S Pieper, Jean-Pierre Bassand, A John Camm, David A Fitzmaurice, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Gloria Kayani, Ali Oto, Frank Misselwitz, Jonathan P Piccini, Frederik Dalgaard, Alexander G G Turpie, Freek W A Verheugt, Ajay K Kakkar, for the GARFIELD-AF Investigators.European Heart JournalGARFIELD-AF Risk Score For Mortality, Stroke, and Bleeding Within 2 Years in Patients With Atrial Fibrillation 10.1093/ehjqcco/qcab028
March 11, 2022P.J. Devereaux, M.D., Ph.D., Andre Lamy, M.D., Matthew T.V. Chan, M.B., B.S., Ph.D., René V. Allard, M.D., Vladimir V. Lomivorotov, M.D., Ph.D., Giovanni Landoni, M.D., Hong Zheng, Ph.D., Domenico Paparella, M.D., Michael H. McGillion, R.N., Ph.D., Emilie P. Belley-Côté, M.D., Ph.D., Joel L. Parlow, M.D., Malcolm J. Underwood, M.D., et al., for the VISION Cardiac Surgery Investigators†.NEJMHigh-Sensitivity Troponin I After Cardiac Surgery and 30-Day Mortality 10.1056/NEJMoa2000803
February 25, 2022Michael Walsh, Claudette Bethune, Andrew Smyth, Jessica Tyrwhitt, Shiangtung W. Jung, Rosie Z. Yu, Yanfeng Wang, Richard S. Geary, Jeffrey Weitz, Sanjay Bhanot, on Behalf of theCS4 InvestigatorsClinical ResearchPhase 2 Study of the Factor XI Antisense Inhibitor IONIS-FXIRx in Patients With ESRD 10.1016/j.ekir.2021.11.011

February 18, 2022

Thirunavukkarasu Sathish, Prof Koon K Teo, Prof Philip Britz-McKibbin, Biban Gill, Shofiqul Islam, Prof Guillaume Paré, et al.

 

The Lancet

 

Variations In Risks From Smoking Between High-Income, Middle-Income, and Low-Income Countries: An Analysis of Data From 179 000 Participants From 63 Countries 10.1016/S2214-109X(21)00509-X
February 11, 2022Paul F. Lebeau, Jae Hyun Byun, Khrystyna Platko, Paul Saliba, Matthew Sguazzin, Melissa E. MacDonald, Guillaume Paré, Gregory R. Steinberg, Luke J. Janssen, Suleiman A. Igdoura, Mark A. Tarnopolsky, S. R. Wayne Chen, Nabil G. Seidah, Jakob Magolan & Richard C. Austin.Nature CommunicationsCaffeine Blocks SREBP2-Induced Hepatic PCSK9 Expression To Enhance LDLR-Mediated Cholesterol Clearance 10.1038/s41467-022-28240-9
January 28, 2022Patricia Hewston, Courtney Kennedy, George Ioannidis, Dafna Merom, Genevieve Hladysh, Sharon Marr, Justin Lee, Richard Sztramko, Laurel Trainor, Amanda Grenier, Matthew Harold Woolhouse, Christopher Patterson & Alexandra PapaioannouBMCDevelopment of GERAS DANcing for Cognition and Exercise (DANCE): a feasibility study 10.1186/s40814-021-00956-3
January 21, 2022Mukul Sharma, Eric E. Smith, Lesly A. Pearce, Ashkan Shoamanesh, Kanjana S. Perera, Shelagh B. Coutts, Dorte Damgaard, Sebastian F. Ameriso, Joung-Ho Rha, Boris Modrau, Byung-Woo Yoon, Marina Romano, Steven R. Messé, Jessica Barlinn, Johann Lambeck, Feryal Saad, Scott D. Berkowitz, Hardi Mundl, Stuart J. Connolly, and Robert G. Hart and on behalf of the NAVIGATE ESUS MIND MRI Substudy Investigators

 

Stroke

Frequency and Patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial 10.1161/STROKEAHA.120.032976

January 14, 2022
Ali Zhang, Jessica A. Breznik, Rumi Clare,  Ishac Nazy,  Matthew S. Miller,  Dawn M. E. Bowdish,  Andrew P. CostamedRxivAntibody Responses to 3rd Dose mRNA Vaccines in Nursing Home and Assisted Living Residents 10.1101/2021.12.17.21267996
December 17, 2021Sharon Yeunga, Mark Rosenbergb, Donna Banach, Lisa Mayottee, Sonia S.Anand, Lac La Ronge Indian Band, Fort McKay First Nation, HeatherCastledenSSM - Population HealthBonding social capital and health within four First Nations communities in Canada: A cross-sectional study 10.1016/j.ssmph.2021.100962

 

December 3, 2021

Allison E. Kennedy, Laura Cook, Jessica A. Breznik, Braeden Cowbrough, Jessica G. Wallace, Angela Huynh, James W. Smith, Kiho Son, Hannah Stacey, Jann Ang, Allison McGeer, Brenda L. Coleman, Maggie Larché, Mark Larché, Nathan Hambly, Parameswaran Nair, Kjetil Ask, Matthew S. Miller, Jonathan Bramson, Megan K. Levings, Ishac Nazy, Sarah Svenningsen, Manali Mukherjee, Dawn M. E. BowdishVirusesLasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections 10.3390/v13112239
November 26, 2021RECOVERY Collaborative GroupCOVID-19Aspirin in Patients Admitted to Hospital with COVID-19 (RECOVERY): A Randomised, Controlled, Open-Label, Platform Trial  10.1016/S0140-6736(21)01825-0

November 19, 2021

Seung Mi Yoo, Vivan W C Lau, Craig Aarts, Bojana Bojovic, Gregory Steinberg, Joanne A Hammill, Anna Dvorkin-Gheva, Raja Ghosh, Jonathan L BramsonOncoImmunology Manufacturing T Cells in Hollow Fiber Membrane Bioreactors Changes Their Programming and Enhances Their Potency  10.1080/2162402X.2021.1995168
November 12, 2021Matthew Sibbald, Natalia Pinilla-Echeverri, Mognee Alameer , Jorge Chavarria, Gustavo Dutra, Tej ShethCOVID-19 Using Optical Coherence Tomography to Identify Lipid and Its Impact on Interventions and Clinical Events - A Scoping Review 10.1253/circj.CJ-21-0377
October 29, 2021

Alyson Takaoka, Benjamin Tam, Meredith Vanstone, France J. Clarke, Neala Hoad, Marilyn Swinton, Feli Toledo, Anne Boyle, Anne Woods, Erick H. Duan, Diane Heels-Ansdell, Lily Waugh, Mark Soth, Jill Rudkowski, Waleed Alhazzani, Dan Perri, Tania Ligori, Roman Jaeschke, Nicole Zytaruk & Deborah J. Cook. 

BMC Health Services Research

Scale-up and Sustainability of a Personalized End-of-Life Care Intervention: A Longitudinal Mixed-Methods Study 10.1186/s12913-021-06241-6#Sec19 

October 22, 2021Arian Ghassemian, Jane Jiyoon Park, Michael W. Tsoulis & Harold Kim.  Allergy, Asthma & Clinical ImmunologyTargeting the IL-5 Pathway in Eosinophilic Asthma: A Comparison of Mepolizumab to Benralizumab in the Reduction of Peripheral Eosinophil Counts 10.1186/s13223-020-00507-0
October 14, 2021Netusha Thevaranjan, Alicja Puchta, Christian Schulz, Avee Naidoo, J C Szamosi, Chris P Verschoor, Dessi Loukov, Louis P Schenck, Jennifer Jury, Kevin P Foley, Jonathan D Schertzer, Maggie J Larché, Donald J Davidson, Elena F Verdú, Michael G Surette, Dawn M E Bowdish.  
Authors: Netusha Thevaranjan, Alicja Puchta, Christian Schulz, Avee Naidoo, J C Szamosi, Chris P Verschoor, Dessi Loukov, Louis P Schenck, Jennifer Jury, Kevin P Foley, Jonathan D Schertzer, Maggie J Larché, Donald J Davidson, Elena F Verdú, Michael G Surette, Dawn M E Bowdish.
Cell Host & Microbe Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction 10.1016/j.chom.2017.03.002
October 8, 2021Philippe Bégin, Jeannie Callum, Donald M. Arnold et al.TrialsConvalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial  10.1186/s13063-021-05235-3 
October 1, 2021Tao Chen, Amy Po Yu Tsai, Seo Am Hur, Alyson W. Wong, Mohsen Sadatsafavi, Jolene H. Fisher, Kerri A. Johannson, Deborah Assayag, Julie Morisset, Shane Shapera, Nasreen Khalil, Charlene D. Fell, Helene Manganas, Gerard Cox, Teresa To, Andrea S. Gershon, Nathan Hambly, Andrew J. Halayko, Pearce G. Wilcox, Martin Kolb & Christopher J. RyersonRespiratory ResearchValidation and minimum important difference of the UCSD Shortness of Breath Questionnaire in fibrotic interstitial lung disease  10.1186/s12931-021-01790-0
September 24, 2021Paul Oykhman, Fernando Aleman Paramo, Prof Jean Bousquet, David W. Kennedy, Romina Brignardello-Petersen, Derek K. Chu Allergy & Clinical ImmunologyComparative Efficacy and Safety of Monoclonal Antibodies and Aspirin Desensitization for Chronic Rhinosinusitis with Nasal Polyposis: A Systematic Review and Network Meta-Analysis: DOI:https://doi.org/10.1016/j.jaci.2021.09.009
September 17, 2021Philippe Bégin, Jeannie Callum, Donald M. Arnold Nature MedicineConvalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial: https://www.nature.com/articles/s41591-021-01488-2
September 10, 2021Teresa M Chan; Brandon Ruan; Daniel Lu; Mark Lee; Yusuf YilmazAcademic medicineSystems to support scholarly social media: a qualitative exploration of enablers and barriers to new scholarship in academic medicine   DOI: https://doi.org/10.36834/cmej.72490
September 3, 2021P. Joseph, G.Roshandel, P. Gao, P. Pais, E. Lonn, D. Xavier, A. Avezum, J. Zhu,
L. Liu, K. Sliwa, H. Gamra, S. Bangdiwala, K. Teo, R. Diaz, A. Dans, P. Lopez-Jaramillo, D. Prabhakaran, J M. Castellano, V.Fuster, A. Rodgers, M. Huffman, 
J. Bosch, G. Dagenais, R. Malekzadeh, S. Yusuf
Cardiovascular diseaseFixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis 
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01827-4/fulltext

August 13, 2021

S. Shah, A. Tepler, C. Chung, G. Suarez, R. Peek Jr, A. Hung, C. Roumie, N. Narula

AGA

Host genetic determinants associated with Helicobacter pylori eradication treatment failure: A systematic review and meta-analysis  doi: 10.1053/j.gastro.2021.07.043.

July 30, 2021

N. Narula, E. Wong, M. Dehghan, A. Mente, S. Rangarajan, F. Lanas, P. Lopez-Jaramillo, P. Rohatgi, P. Lakshmi, R. Varma, A. Orlandini, A. Avezum, A. Wielgosz, P. Poirier, M. Almadi, Y. Altuntas, K. Keat Ng, J. Chifamba, K. Yeates, T. Puoane, R. Khatib, R. Yusuf, K. Boström, K. Zatonska, R. Iqbal, L. Weida, Z. Yibing, L. Sidong, A. Dans, A. Yusufali, N. Mohammadifard, J. Marshall, P. Moayyedi, W. Reinisch, S. YusufBJMAssociation of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study doi: 10.1136/bmj.n1554

July 16, 2021

V. Goel, D. Bulir, E. De Prophetis, M. Jamil, L. Rosella, D. Mertz, C. Regehr, M. Smieja

BJM

COVID-19 International Border Surveillance at Toronto's Pearson Airport: A Cohort Study doi: 10.1136/bmjopen-2021-050714

July 9, 2021

R. Whitlock, E. Belley-Cote, D. Paparella, J. Healey, K.Brady, M. Sharma, W. Reents, P. Budera, A. Baddour, P. Fila, P.J. Devereaux, A. Bogachev-Prokophiev, A. Boening, K. Teoh, G. Tagarakis, M. Slaughter, A. Royse, S. McGuinness, M. Alings, P. Punjabi, C. D. Mazer, R. Folkeringa, A. Colli, Á. Avezum, J. Nakamya, K. Balasubramanian, J. Vincent, P. Voisine, A. Lamy, S. Yusuf, S. Connolly

 

NEJM

 

Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke  doi/10.1056/NEJMoa2101897

June 25, 2021

D. Conen, M. Wang, P J Devereaux, R. Whitlock, W. McIntyre, J. Healey, F. Yuan, S. Yusuf, A. Lamy

JAHA

New-Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Risk of Adverse Events: An Analysis From the CORONARY Trial doi/10.1161/JAHA.120.020426

June 18, 2021

 

A. Bourguignon, D. Arnold, T. Warkentin, J. Smith, T. Pannu, J. Shrum, Z. Al Maqrashi, A. Shroff, M. Lessard, N. Blais, J.Kelton, and I.Nazy

 

NEJM

 

 

Adjunct Immune Globulin for Vaccine-Induced Thrombotic Thrombocytopenia
doi: 10.1056/NEJMoa2107051

June 11, 2021G. Juneja, M. Castelo, C. Yeh, S. Cerroni, B. Hansen, J. Chessum, J. Abraham, E. Cani, D. Dwivedi, D. Fraser, M. Slessarev, C. Martin, S. McGilvray, P. Gross, P. Liaw, J. Weitz, P. KimJTHBiomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID-19: A single-center prospective longitudinal study   doi.org/10.1111/jth.15327
June 4, 2021A. Shoaib, H. Van Spall, J. Wu, J. Cleland, T. McDonagh, M. Rashid, M. Mohamed, F. Ahmed, J. Deanfield, M. de Belder, C. Gale, M. MamasEHJSubstantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic  doi.org/10.1093/ehjqcco/qcab040


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