Publication of the Month

February 2022Léna Rivard, Leif Friberg, David Conen, Jeffrey S. Healey et al.CirculationAtrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration 10.1161/CIRCULATIONAHA.121.055018
January 2022Philippe Bégin, Jeannie Callum, …Donald M. Arnold et al.nature medicine Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial 10.1038/s41591-021-01488-2
December 2021M. Racey, M. Markle-Reid, D. Fitzpatrick-Lewis, M. U. Ali, H. Gagne, S. Hunter, J. Ploeg, R. Sztramko, L. Harrison, R. Lewis, M. Jovkovic & D. Sherifali BMC GeriatricsFall prevention in community-dwelling adults with mild to moderate cognitive impairment: a systematic review and meta-analysis 10.1186/s12877-021-02641-9
November 2021Connie N.Hess, MHSabManesh R.Patel, Rupert M.Bauersachs, Sonia S.Anand,  et al.Journal of the American College of CardiologySafety and Effectiveness of Paclitaxel Drug-Coated Devices in Peripheral Artery Revascularization: Insights From VOYAGER PAD 10.1016/j.jacc.2021.08.052
October 2021Matt Sibbald, Sandra Monteiro, Jonathan Sherbino, Andrew LoGiudice, Charles Friedman, Geoffrey NormanBMJ JournalsShould electronic differential diagnosis support be used early or late in the diagnostic process? A multicentre experimental study of Isabel 10.1136/bmjqs-2021-013493
September 2021Kollengode Ramanathan, Kiran Shekar, Ryan Ruiyang Ling, Ryan P. Barbaro, Suei Nee Wong, Chuen Seng Tan, Bram Rochwerg, et al. Critical CareExtracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis 10.1186/s13054-021-03634-1
August 2021P. Joseph, G.Roshandel, P. Gao, P. Pais, E. Lonn, D. Xavier, A. Avezum, J. Zhu,
L. Liu, K. Sliwa, H. Gamra, S. Bangdiwala, K. Teo, R. S. Yusuf et al.
Cardiovascular disease

Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis


July 2021V. Goel, D. Bulir, E. De Prophetis, M. Jamil, L. Rosella, D. Mertz, C. Regehr, M. SmiejaCOVID-19COVID-19 international border surveillance at Toronto's Pearson Airport: a cohort study. 2021 Jul 1 DOI: 10.1136/bmjopen-2021-050714
June 2021H. Gerstein, N. Sattar, J. Rosenstock, C. Ramasundarahettige, R. Pratley, R. Lopes, C. Lam, N. Khurmi, L. Heenan, S. Del Prato, L. Dyal, K. BranchDiabetesCardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes. 2021 Jun 28 DOI: 10.1056/NEJMoa2108269
May 2021T. O'Shea, C. Bodkin, V. Mokashi, K. Beal, J. Wiwcharuk, R. Lennox, D. Guenter, M. Smieja, D. Bulir, S. Chong Clin Infect DisPandemic Planning in Homeless Shelters: A Pilot Study of a Coronavirus Disease 2019 (COVID-19) Testing and Support Program to Mitigate the Risk of COVID-19 Outbreaks in Congregate Settings. 2021 May 4. DOI: 10.1093/cid/ciaa743 
April 2021K. Xu, K. de Wit, C. Kearon, S. ParpiaJ Thromb Haemost
A simplified decision rule to rule out deep vein thrombosis using clinical assessment and D-dimer. J Thromb Haemost. 2021 Apr 8. doi: 10.1111/jth.15337.
March 2021P. Roshanov, D. Sessler, M.W. Walsh, L. Thabane, PJ Devereaux et al.Can J CardiolPredicting myocardial injury and other cardiac complications after elective noncardiac surgery with the Revised Cardiac Risk Index: the VISION study. Can J Cardiol. 2021 Mar 23:S0828-282X(21)00164-1. doi: 10.1016/j.cjca.2021.03.015.
February 2021

I. Nazy, S. Jevtic, J. Moore, A. Huynh, J. Smith, J. Kelton & D. Arnold


M. Wang, Z. Chen, M. Wong, L. Thabane, L. Mbuagbaw, D. Siegal, G. Le Gal & A. Holbrook

J Thromb Haemost





Thromb Res

Platelet-activating immune complexes identified in critically ill COVID-19 patients suspected of heparin-induced thrombocytopenia. J Thromb Haemost. 2021 Feb 27.

doi: 10.1111/jth.15283.



Are the correct outcomes being measured in studies of oral anticoagulants? A systematic survey. Thromb Res. 2021 Feb 18;201:30-49. doi: 10.1016/j.thromres.2021.02.016



January 2021

H. Neighbour, S. Monteiro, M. Lee, Y. Wu, A. Levinson, J. Sherbino


S. Yusuf, P. Joseph, A. Dans, P. Gao, K. Teo, D. Xavier, P. López-Jaramillo, K. Yusoff, A. Santoso, the International Polycap Study 3 Investigators et al.

J Gen Intern Med




N Engl J Med

Effect of Gender on Feedback Associated with a Direct Clinical Observation Tool Used during Clerkship at McMaster University. J Gen Intern Med. 2021 Jan 27. doi: 10.1007/s11606-020-06399-5.




Polypill with or without Aspirin in Persons without Cardiovascular Disease. 2021 Jan 21;384(3):216-228. doi: 10.1056/NEJMoa2028220.

December 2020P. Hewston, CC Kennedy, S. Borhan, D. Merom, P. Santaguida, G Ioannidis, S. Marr, N. Santesso, L. Thabane, S. Bray, A PapaioannouAge AgeingEffects of dance on cognitive function in older adults: a systematic review and meta-analysis. 2020 Dec 19:afaa270.
November 2020W. Alhazzani, D. Cook, G. Guyatt et al.Intensive Care MedEfficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: an updated systematic review and network meta-analysis of randomized trials. 2020 Nov;46(11):1987-2000.
October 2020

M. Jeyanathan, S. Afkhami, F. Smaill, MS Miller, BD Lichty, Z Xing


M. Sharma M, RG Hart, JW Eikelboom, EM Lonn, S. Yusuf et al.

Nat Rev Immunol





Immunological considerations for COVID-19 vaccine strategies. 2020 Oct;20(10):615-632.




Rivaroxaban for Prevention of Covert Brain Infarcts and Cognitive Decline: The COMPASS MRI Substudy. 2020 Oct;51(10):2901-2909.

September 2020CM Clase, M. Joseph, MB Dolovich et al. Ann Intern MedCloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach.2020 Sep 15;173(6):489-491.
August 2020

G. Pare, M. Sharma, A. Shoamanesh et al. 


D. Arnold, N. Heddle, E. Jamula, W. Lim, J. Kelton, et al.





Lancet Haematol

High-Sensitivity Cardiac Troponin T for Risk Stratification in Patients With Embolic Stroke of Undetermined Source. 2020 Aug;51(8):2386-2394.



Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial. 2020 Sep;7(9):e640-e648.

July 2020M. Zworth, C. Saleh, I. Ball, G. Kalles, S. Oczkowski et al. BMJ OpenProvision of Medical Assistance in Dying: a Scoping Review
2020 Jul 8;10(7):e036054.

June 2020

S. Mithoowani, A. Cervi, N. Shah, E. Sirotich, I. Nazy, D. Arnold et al. 
J Thromb Haemost

Management of Major Bleeds in Patients With Immune Thrombocytopenia. 2020 Jul;18(7):1783-1790.

May 2020

M. Mukherjee, A. Bhalla, J. Cherukat, H. Al-Hayyan, A. Ayoub, P. Nair et. al. Eur Respir J

Sub-optimal Treatment Response to anti-IL-5 Monoclonal Antibodies in Severe Eosinophilic Asthmatics With Airway Autoimmune Phenomena. Eur Respir J. 2020 May 22;2000117.


April 2020

Drs. S. Anand, K. Schulze, K. Teo, S. YusufStrokeReduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging-Detected Vascular Brain Injury. Stroke. 2020 Apr;51(4):1158-1165.
Dr. I. Walker et al.




Drs. M. Pigeyre, S. Yusuf, H. Gerstein, G. Paré et al.

Lancet Hematology




Diabetes Care

Addition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with Haematological malignancies undergoing transplantation from unrelated donors; final analysis of a randomised, open-label, multicentre, phase 3 trial. Lancet Hematol.

2020 Feb;(7)2:e100-e111.


ACE and Type 2 Diabetes Risk: A Mendelian Randomization Study. Diabetes Care. 2020 Feb 4. pii: dc191973.

Dr. G. Steinberg et al.Nat Rev Drug DiscovAMP-activated protein kinase: the current landscape for drug development. Nat Rev Drug Discov. 2019;18(7):527-551.
Drs. C. Kearon, K. de Wit, S. Schulman, F. Spencer, S. Bates et al.


Drs. A. Patel, F. Borges, G. Guyatt, W. Szczeklik, A. Garg, M. Walsh, S. Yusuf, PJ Devereaux et al.






Ann Intern Med

Diagnosis of Pulmonary Embolism with D-Dimer Adjusted to Clinical Probability. N Engl J Med. 2019 Nov 28;381(22):2125-34.



Preoperative N-Terminal Pro-B Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. 2020 Jan 21;172(2):96-104.



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