Research activity and funding support have been broadly based in the areas of metabolic bone disease, lupus, scleroderma, inflammatory arthritis, and vasculitis.
Multiple grants have been supported by CIHR, HAHSO Innovation Fund, NIH, The Arthritis Society, The Canadian Rheumatology Association as well as industry partners.
Collaboration with Radiology, Respirology, Nephrology, Geriatrics, Engineering and Rehabilitation Sciences has continued.
Dr. Rick Adachi’s work continues to be recognized internationally as one of the most published faculty at St. Joseph’s Health Care. He has several peer-reviewed grants.
Dr. Khalidi continues to be very productive in expanding work in new treatments for vasculitis with NIH and industry funding.
Dr. Larché continues her work in Scleroderma and imaging in inflammatory arthritis.
Dr. Khalidi remains the Vice-President of CanVasc (Canadian Vasculitis Research Network). He is involved in numerous international research projects in Vasculitis (VCRC/PEXIVAS/DCVAS).
Dr. Kim Legault continues to work on several research projects including guidelines in SLE and CAPS, and the cohort study rivaroxaban in antiphospholipid syndrome. This has led to the publication of new guidelines for CAPS and Lupus.
Dr. Mark Matsos is an investigator in the LuCIN (Lupus clinical investigator network) and co-author of new Lupus guidelines.
Our fourth annual Clinical Day in Rheumatology was extremely successful.
New Fellowships in Vasculitis and Scleroderma have been established.
New faculty recruitment; Dr. Stephanie Garner having completed a Vasculitis and Rare Disease fellowship and Dr. Kostas Tselios having extensive experience in Lupus Clinical research .
Clinical Scholars Dr. Faiza Khokhar and Dr. Mary-Clair Yelovich supported by the division in completing their Master’s in Education and Quality Improvement respectively.
Fellows within the Division of Rheumatology are enrolled in the Hospital for Special Surgery Class-Rheum® research training curriculum. This program teaches study design through a problem-based approach that is specific to rheumatology. Fellows work through modules and participate in moderated tutorial discussions throughout their training period and have found it to be very helpful for the preparation of their exams and conducting their own research.
The Rheumatology Research program for trainees continues to build on its strengths of the past. Research projects are focused on the clinical interests of trainees and give trainees opportunities to expand their knowledge and skills in study design, methodology, data analysis and scientific writing. Types of research currently underway in the Division of Rheumatology include large database analyses, retrospective chart reviews, cross-sectional studies and prospective longitudinal cohort studies. Rheumatology fellows, internal medicine residents, medical students and undergraduate students often work collaboratively on projects to increase research capacity and optimize efficiency. Not only do our research studies span the spectrum of clinical areas in Rheumatology (Scleroderma, Vasculitis, Rheumatoid Arthritis, etc.,) but they often take advantage of expertise in other areas of medicine including geriatrics, respirology and nephrology. The adult Division of Rheumatology has an excellent relationship with our pediatric rheumatology colleagues at McMaster Children’s Hospital which has resulted in research that investigates the transition of patients from pediatric to adult rheumatology care. Over the past year, our research trainees have included 6 fellows, 13 residents, 9 medical students and 7 undergraduate/graduate students. Our trainees have successful track records of presenting abstracts and oral presentations at national and internal conferences, many of whom have been recognized with awards for their work.
Currently our research has focussed in 3 major areas including:
This has been accomplished through major collaborations with GERAS under the leadership of Dr. Alexandra Papaioannou, with the University of Toronto examining imaging in osteoarthritis under Dr. Andy Kin on Wong and atypical femoral fractures with Dr. Angela Cheung, and a hip fracture prediction tool in long-term care with Dr. George Ioannidis and Dr. Papaioannou, and a novel imaging tool using DEXA to predict hip fracture that was developed in collaboration with the department of engineering under Dr. Cheryl Quenneville.
Frailty and sarcopenia are new areas of research that take advantage of many of the tools that were developed by us here at McMaster. As is evident, we have been able to take advantage of this and are currently participating in many funded research projects.
We are examining the effects of muscle-bone interaction in a longitudinal CIHR funded study of knee osteoarthritis. We are also examining the effects of prehab in those who are undergoing joint replacement.
Finally, we continue to collaborate with the GERAS centre in the development of tools to identify those at greatest risk for hip fracture having developed the “Fracture Risk Scale” for both Long-term Care and Home Care residents and in our work headed up by our engineering colleagues in refining DEXA measurements with the development of new software to predict hip fractures. Clinically Dr. Lau has headed up research in collaboration with the transplant nephrologists in the prevention of bone loss with either a bisphosphonate or denosumab.
2018-22 A Papaioannou, J. Adachi, L Dolovich, P Hewston, G Ioannidis, C Kennedy, J Lee, D Mangin, S Marr, A Negm, D O'Reilly, K Rockwood, L Thabane. Frailty rehabilitation: A community-based program to promote healthy aging. CIHR 4 years. $696,152
2018-20 A. Papaioannou, A. Negm, C. Kennedy, G. Ioannidis, J. Lee, L. Thabane, JD. Adachi, S. Marr, A. Lau, S. Atkinson, J. De Beer, M. Winemaker, V. Avram, B. Deheshi, D. Williams, D. Armstrong, B. Lumb, A. Panju, J. Richardson. Multimodal Pre-Habilitation for Frail Patients: The Fit-Joints Randomized Controlled Trial. Physician Services Incorporated (PSI). Health Research Project. Dec2018-Nov 2020 $199,733.
2018-19 A. Papaioannou, JD. Adachi, L. Giangregorio, J. Hirdes, G. Ioannidis, S. Jaglal, S.Kaasalainen, C. Kennedy. Developing a fracture risk clinical assessment protocol for home and long-term care. Canadian Institute of Health Research (CIHR). Planning and Dissemination Grant -Institute Community Support. $22,875.
2019-25 Wong AKO, Cheung A, Adachi J, Bobba R, Giangregorio L, Lau A, Mohankumar R, Papaioannou A, Probyn L, Sussman M. Poor muscle-bone quality and its downstream impact on knee osteoarthritis disease development in postmenopausal women: the Appendicular Muscle and Bone Extension Research Study (AMBERS). CIHR 6 years $654,077
2020-22 Papaioannou A, Adachi JD, Hewston P, Ioannidis G, Kennedy C, Lee J, Marr S, McArthur C, Noseworthy M. Changing the trajectory and treatment of sarcopenia in older adults: A randomized control trial. HAHSO AFP Innovation Grant Competition 2019/2020. $199 752.48
2020-21 Papaioannou A, Adachi JD, Giangregorio L, Griffith L, Ioannidis G, Lee J, Leslie W, McArthur C, Morin S, Thabane L. Cognition, frailty and falls: Should they be part of fracture risk assessment? CIHR Catalyst grant-Analysis of CLSA data. $68,525 Start date 1/Mar/2020; End date 28/2/2021
2020 Fisher, P (PI), Kennedy, C (Co-PI), Papaioannou, A, Ioannidis, G, Hanman, A, Hewston, P, Adachi, JD. Reliability and Validity of the Fit-Frailty App in Older Adults, Hamilton Health Sciences, Clinical Health Professional Investigator Operating Grant, Jan-December 2020, $15,000.
2020-21 Papaioannou A, Adachi JD, Armstrong D, Bray S, de Wit K, Hewston P, Ioannidis G, Kennedy C, Kodis J, Lee J, Mangin D, Marr S, McArthur C, Misiaszek B, Patterson C, Woo T. Funding Name: McMaster COVID-19 Research Fund (Stream 1 – Research with Immediate Impact. Project Title: GERAS Frailty Rehabilitation at Home: Virtual bundled care for seniors who are frail to build strength and resilience during COVID-19. Funding Duration: June 1, 2020 – May 31, 2021. $134,932
In collaboration with Dr Karen Beattie, Dr George Ioannidis, I have 3 main areas of research interest: (1) imaging in early rheumatoid arthritis (2) exploring the immunology of rheumatoid arthritis (RA) and systemic sclerosis (SSc), and (3) participating in multiple cohort studies – CSRG, SPIN, CIMS, OBRI, BIODAM, CATCH, ReacCh and STOPP.
The foot imaging study was started in 2013 with an investigator initiated study grant. This study uses ultrasonography and other imaging to determine disease activity in patients with early rheumatoid arthritis. With my group, we have presented >20 abstracts at national and international meetings, with 3 podium presentations at the American College of Rheumatology highlighting some of the findings of that study.
We have identified particular proteins which may trigger the immune activation in both RA and SSc. The next steps in this basic science research is to test the particular proteins in peripheral blood mononuclear cells (PBMCs) from patients with these autoimmune diseases.
Through collaboration with Drs Ishac Nazi and Mark Larché, we are exploring the role of platelet activation in SSc. To date we have found increased levels of Platelet Factor 4 (PF4) in patients compared with controls.
I have > 100 peer reviewed publications with over 30 in the past 3 years. I have had significant research funding with >$1.2 million as principal investigator and >$1.4 million as co-investigator through the Department of Medicine.
During my PhD thesis work, I was privileged to have a first author paper looking at the role of cytokines in asthma. This was published in the Lancet and has become a “citation classic” (maiden name, Leckie).
Research funding (past 5 years)
2018 Oct - 2021 Oct Dr Mark Larche, Dr Ishac Nazi, Dr Maggie Larche, Validation of CXCL4 as a therapeutic target in scleroderma, Grant, Hamilton Scleroderma Group, Research - New Project, $25,000.00
2017 Feb - 2021 Dec Dr Mark Larche, Dr Derek Haaland Dr Maggie Larche, Development of peptide immunotherapy for scleroderma : Identification of T cell epitopes from autoantigens, Grant, Scleroderma Society of Canada, Research - New Project, $30,000.00
2015 Jun - 2020 Jun Dr. Mark Larché and Dr. Elena Tonti, Dr Maggie Larche, Dr. B. Duvvuri and Dr. D Haaland, Development of peptide immunotherapy for Rheumatoid Arthritis: Identification and validation of T cell epitopes from citrullinated auto-antigens., Grant, CHIR, Research - No subtype specified, $98,462.00
2017 Jan - 2018 Dec Dr Maggie Larche, Dr Karen Beattie, Foot imaging in Rheumatoid Arthritis - 2 year follow up study, Grant, Abbvie, Research - New Project, $50,000.00
2012 Dec - 2018 Dec Dr Maggie Larche, Dr Gerard Cox, Dr Nader Khalidi, Dr Mark Larche, Dr Kjetil Ask, Dr Martin Kolb, Dr Peter Margetts, Hamilton Scleroderma Group, Grant, Scleroderma Society of Canada, Research - New Project, $490,000.00
2012 Dec - 2018 Sep Dr Maggie Larche, Foot imaging in RA study., Grant, Abbvie, Research - First Time, $486,526.00
2015 Oct - 2018 Oct Thombs, Brett D, Baron, Murray; Bartlett, Susan J; Boutron, Isabelle; Cuijpers, Pim; Fortin, Paul R; Gottesman, Karen; Hudson, Marie; Johnson, Sindhu R; Kwakkenbos, Linda; Larché, Maggie J; Malcarne, Vanessa; Mayes, Maureen; Mouthon, Luc; Poiraudeau, Serge; Pope, Janet E; Riper, Heleen; Ruwaard, Jeroen; Sauve, Maureen; Schouffoer, Anne M; Steele, Russell J; Welling, Joep; Wigley, Fred, Randomized Controlled Trail of an Internet-based Scleroderma Self-Management Program: A Scleroderma patient-Centered Intervention Network (SPIN) Study, Grant, Canadian Institute of Health Research, Research - New Project, $561,909.00
2016 Jul - 2017 Jun Thombs, Brett D; Mouthon, Luc; Poiraudeau, Serge, Baron, Murray; Bartlett, Susan J; Boutron, Isabelle; Cuijpers, Pim; Fortin, Paul R; Gottesman, Karen; Hudson, Marie; Johnson, Sindhu R; Khanna, Dinesh; Kwakkenbos, Linda; Larché, Maggie J; Malcarne, Vanessa; Mayes, Maureen; Poole, Janet L; Pope, Janet E; Riper, Heleen; Ruwaard, Jeroen; Sauve, Maureen; Schouffoer, Anne M; Steele, Russell J; Van den Ende, Cornelia; Welling, Joep; Wigley, Fred, Randomized Controlled Trial of an Internet-based Exercise Program to Improve Hand Function in Patients with Scleroderma: A Scleroderma Patient-Centered Intervention Network (SPIN) Study, Grant, Canadian Institute of Health Research, Research - New Project, $100,000.00
Dr. Khalidi’s main focus of research has been in Vasculitis and Scleroderma.
He is a Co-Investigator and Steering Committee Member of the Vasculitis Clinic Research Consortium (VCRC) and recruits patients for its North American Clinical Trials Cohort and Databas that includes the University of Toronto and other sites such as Boston University, Cleveland Clinics, University of Pennsylvania and the Mayo Clinic. He is involved in numerous international research projects in Vasculitis as part of the VCRC. He is the Vice President and Co-Founder of CanVasc the Canadian network for research in vasculitides. He is currently also involved in local research to assess the role of MRI of temporal arteries versus temporal artery biopsy in Giant Cell Arteritis as well as many other clinical research projects.
He has been involved with the Canadian Scleroderma Research Study Group (CSRG) along with its database and is actively recruiting patients for the national database since 2007. He has been involved in numerous local and national research projects in Scleroderma as part of the CSRG. He is an executive member of the Hamilton Scleroderma Group that strives for excellence in research and education in Scleroderma in Hamilton and its surrounding areas in particular.
ARAMIS & CUTIS Pilot Studies: A randomized multicenter study for isolated skin vasculitis
Funding Sources: 2016/1 - 2021/8 University of Pennsylvania Total Funding - 5,250 (United States dollar)
VCRC Tissue Repository Collection Funding Sources: 2016/8 - 2021/8 University of Pennsylvania Total Funding - 15,336 (United States dollar)
Vasculitis Clinical Research Consortium Database, National Institutes of Health
Funding Sources: 2014/8 - 2021/7 Foundation for the National Institutes of Health (FNIH) Vasculitis Clinical Research Consortium Total Funding - 132,695 (Canadian dollar)
Novel Methods for the Conduct of Clinical Trials (in Vasculitis) VCRC Principal
Funding Sources: 2013/6 - 2016/6 Foundation for the National Institutes of Health (FNIH) Total Funding - 3,240 (Canadian dollar)
Adaptation and Validation of PROMIS for use in Vasculitis, Vasculitis Clinical Research Consortium (VCRC)
Funding Sources: 2012/9 - 2021/9 National Institutes of Health Vasculitis Clinical Research Consortium Total Funding - 4,909 (Canadian dollar)
Canadian Scleroderma Research Group Database Funding Sources: 2014/7 - 2021/6 Scleroderma Society of Ontario Total Funding - 15,000 (Canadian dollar) per year
Ontario Best Practices Research Initiative (OBRI) Funding Sources: 2015/7 - 2021/6 Ontario Best Research Initiative OBRI Total Funding - 25,000 (Canadian dollar)
Randomized controlled trial comparing rituximab with azathioprine as maintenance therapy in relapsing ANCA-associated vasculitis (RITAZAREM)
Funding Sources: 2014/1 - 2021/8 Cambridge University Hospitals NHS Foundation Trust, National Institutes of Health RITAZAREM Total Funding - 100,000 (Canadian dollar)
Abatacept for the Treatment of Relapsing, Non-Severe Granulomatosis with Polyangiitis (ABROGRATE) Funding Sources: 2014/3 - 2021/7 Cleveland Clinic Foundation ABROGATE Total Funding - 50,000 (Canadian dollar)
The Scleroderma Patient-centred Intervention Network Funding Sources: 2014/7 - 2021/6 Scleroderma Society of Canada Total Funding - 5,000 (Canadian dollar)
Diagnostic and classification criteria for vasculitis (DCVAS) Funding Sources: 2011/7 - 2018/12 University of Oxford, UK, EUVAS, VCRC DCVAS Total Funding - 1,650 (Canadian dollar)
Abatacept in Giant Cell and Takayasu’s Arteritis, National Institutes of Health.
Funding Sources: 2010/12 - 2015/9 Cleveland Clinic Foundation Total Funding - 46,428 (Canadian dollar)
1. Goel R, Gribbons KB, Carette S, Cuthbertson D, Hoffman GS, Joseph G, Khalidi NA, Koening CL, Kumar S, Langford C, Maksimowicz-McKinnon K, McAlear CA, Monach PA, Moreland LW, Nair A, Pagnoux C,Quinn KA, Ravindran R, Seo P, Sreih AG, Warrington KJ, Ytterberg SR, Merkel PA, Danda D, Grayson PC. (2020). Derivation of an angiographically based classificationsystem in Takayasu's arteritis: an observational study from India and NorthAmerica.Rheumatology (Oxford).59(5): 1118-1127.
2. Donaldson L, Nanji K, Rebello R, Khalidi NA, Rodriguez AR. (2020). Involvement of the intracranial circulation in giant cellarteritis.Can J Ophthalmol.
3. Walsh M, Merkel PA, Peh CA, Szpirt WM, Puéchal X, Fujimoto S, Hawley CM, Khalidi N, Floßmann O, Wald R, Girard LP, Levin A, Gregorini G, Harper L, Clark WF, Pagnoux C, Specks U, Smyth L, Tesar V, Ito-Ihara T, de Zoysa JR, Szczeklik W, Flores-Suárez LF, Carette S, Guillevin L, Pusey CD, Casian AL,Brezina B, Mazzetti A, McAlear CA, Broadhurst E, Reidlinger D, Mehta S, Ives N, Jayne DRW; PEXIVAS Investigators. (2020). Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis. N Engl J Med.382(7): 622-631.
4. Kermani TA, Diab S, Sreih AG, Cuthbertson D, Borchin R, Carette S, Forbess L, Koening CL, McAlear CA, Monach PA, Moreland L, Pagnoux C, Seo P, Spiera RF, Warrington KJ, Ytterberg SR, Langford CA, Merkel PA, Khalidi NA; Vasculitis Clinical Research Consortium. (2019). Arterial lesions in giant cell arteritis: A longitudinal study.Semin Arthritis Rheum. 48(4): 707-713
5. Ing EB, Miller NR, Nguyen A, Su W, Bursztyn LLCD, Poole M, Kansal V, Toren A, Albreki D, Mouhanna JG, Muladzanov A, Bernier M, Gans M, Lee D, Wendel C, Sheldon C, Shields M, Bellan L, Lee-Wing M, Mohadjer Y, Nijhawan N, Tyndel F, Sundaram ANE, Ten Hove MW, Chen JJ, Rodriguez AR, Hu A, Khalidi N, Ing R, Wong SWK, Torun N. (2019). Neural network and logistic regression diagnostic prediction models for giant cell arteritis: development and validation.Clin Ophthalmol.13: 421-430
6. Aeschlimann FA, Barra L, Alsolaimani R, Benseler SM, Hebert D, Khalidi N, Laxer RM, Noone D, Pagnoux C, Twilt M, Yeung RSM. (2019). Presentation and Disease Course of Childhood-Onset Versus Adult-Onset Takayasu Arteritis.Arthritis Rheumatol. 71(2): 315-323.
7. Mukherjee M, Thomas SR, Radford K, Dvorkin-Gheva A, Davydchenko S, Kjarsgaard M, Svenningsen S, Almas S, Felix LC, Stearns J, Li QZ, Khalidi N, Lacy P, Nair PK. (2019). Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis with Polyangiitis.Am J Respir Crit Care Med.199(2): 158-170.
8. Quinn KA, Gelbard A, Sibley C, Sirajuddin A, Ferrada MA, Chen M, Cuthbertson D, Carette S, Khalidi NA, Koening CL, Langford CA, McAlear CA, Monach PA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Ytterberg SR, Merkel PA, Grayson PC. (2019). Subglottic stenosis and endobronchial disease ingranulomatosis with polyangiitis.Rheumatology (Oxford).58(12): 2203-2211.
9. Gribbons KB, Ponte C, Carette S, Craven A, Cuthbertson D, Hoffman GS, Khalidi NA, Koening CL, Langford CA, Maksimowicz-McKinnon K, McAlear CA, Monach PA, Moreland LW, Pagnoux C, Quinn KA, Robson JC, Seo P, Sreih AG, Suppiah R, Warrington KJ, Ytterberg SR, Luqmani R, Watts R, Merkel PA, Grayson PC. (2019). Patterns of Arterial Disease in Takayasu's Arteritis andGiant Cell Arteritis.Arthritis Care Res (Hoboken).
10. Rina S. Fox Linda Kwakkenbos Marie?Eve Carrier Sarah D. Mills Shadi Gholizadeh Lisa R. Jewett Scott C. Roesch Erin L. Merz Shervin Assassi Daniel E Furst Karen Gottesman Maureen D. Mayes Brett D. Thombs Vanessa L. Malcarne SPIN Investigators (Khalidi, N). (2018). Validation of the Social Appearance Anxiety Scale in Patients with Systemic Sclerosis: A Scleroderma Patient-centered Intervention Network Cohort Study. Arthritis Care Res (Hoboken).
11. Rhéaume M, Rebello R, Pagnoux C, Carette S, Clements-Baker M, Cohen-Hallaleh V, Doucette-Preville D, Stanley Jackson B, Salama Sargious Salama S, Ioannidis G, Khalidi NA. (2017). High-Resolution Magnetic Resonance Imaging of Scalp Arteries for the Diagnosis of Giant Cell Arteritis: Results of a Prospective Cohort Study.Arthritis Rheumatol. 69(1): 161-168.
12. Mukherjee M, Lim HF, Thomas S, Miller D, Kjarsgaard M, Tan B, Sehmi R, Khalidi N, Nair P. (2017). Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy. Allergy Asthma Clin Immunol.13(2)
13. Langford CA, Cuthbertson D, Ytterberg SR, Khalidi N, Monach PA, Carette S, Seo P, Moreland LW, Weisman M, Koening CL, Sreih A, Spiera R, McAlear CA, Warrington KJ, Pagnoux C, McKinnon K, Forbess LJ, Hoffman GS, Borchin R, Krischer JP, Merkel PA; Vasculitis Clinical Research Consortium.. (2017). A randomized, double-blind trial of abatacept (CTLA4-IG) for the treatment of giant cell arteritis. Arthritis Rheumatol.
14. Richard N, Hudson M, Gyger G, Baron M, Sutton E, Khalidi N, Pope JE, Carrier N, Larché M, Albert A, Fortin PR, Thorne C, Masetto A; on the behalf of Canadian Scleroderma Research Group. (2016). Clinical correlates of faecal incontinence in systemic sclerosis: identifying therapeutic avenues. Rheumatology (Oxford).
15. Alsolaimani RS, Bhavsar SV, Khalidi NA, Pagnoux C, Mandzia JL, Tay K, Barra LJ. (2016). Severe Intracranial Involvement in Giant Cell Arteritis: 5 Cases and Literature Review.J Rheumatol.43(3): 648-56.
16. McGeoch L, Twilt M, Famorca L, Bakowsky V, Barra L, Benseler SM, Cabral DA, Carette S, Cox GP, Dhindsa N, Dipchand CS, Fifi-Mah A, Goulet M, Khalidi N, Khraishi MM, Liang P, Milman N, Pineau CA, Reich HN, Samadi N, Shojania K, Taylor-Gjevre R, Towheed TE, Trudeau J, Walsh M, Yacyshyn E, Pagnoux C; Canadian Vasculitis Research Network. CanVasc Recommendations for the Management of Antineutrophil Cytoplasm Antibody-associated Vasculitides. J Rheumatol. 2016 Jan;43(1):97-120.
November 9, 2020
November 9, 2020
September 18, 2020
Five McMaster University professors, all members of the Faculty of Health Sciences, are joining the Canadian Academy of Health Sciences (CAHS) as fellows.
September 15, 2020
It has been a year since the release of the McMaster Textbook of Internal Medicine, and already, it’s been accessed by tens of thousands of people around the world.
September 10, 2020
August 11, 2020
Working together, researchers at McMaster University and the University of Waterloo are searching for how the SARS-CoV-2 virus infects the lungs – and they’re challenging what has become an accepted truth about the virus.
August 5, 2020
Much has been made recently about the new antiviral drug remdesivir for COVID-19 patients, but a McMaster University-led guideline for physicians warns that it would only be used in the most serious cases, and more research is needed.
August 4, 2020
Researchers at McMaster University and the Royal Ontario Museum (ROM) have reported the discovery and diagnosis of an aggressive malignant bone cancer — an osteosarcoma — for the first time ever in a dinosaur.
July 23, 2020
A new McMaster University-based network will bring together researchers and patients to tackle sepsis — a leading cause of death in COVID-19.
July 14, 2020
July 13, 2020
June 25, 2020
McMaster University has garnered $20 million in new funding for 17 COVID-19 research projects from the Canadian Institutes of Health Research (CIHR) and their funding partners.
May 25, 2020
The evidence shows that cloth masks, particularly those with several layers of cotton cloth, block droplet and aerosol contamination of the environment, may reduce transmission of COVID-19.
April 14, 2020
Health sciences and engineering researchers at McMaster University have been racing to assist Woodbridge Foam Corporation in getting a new made-in-Canada mask designed, tested and certified, as supplies of existing medical masks become less certain.
November 15, 2019
New McMaster research has found a program that honours dying patients by fulfilling end of life wishes can be powerful, affordable and sustainable in many settings.
October 24, 2019 by Tina Depko, Health Sciences
The first edition of the McMaster Textbook of Internal Medicine is making its formal debut, fittingly, in time for the 50th anniversary celebrations of the Michael G. DeGroote School of Medicine this month.
August 6, 2019
A Hamilton-led international study of more than 3,000 patients could set the stage globally for how patients can safely use blood-thinning medications before and after surgery to mitigate risk of bleeding and stroke. The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) study was conducted across 23 clinical centres in Canada, United States and Europe.
July 29, 2019
It's the recovery period, not the operating room that is risky for patients undergoing non-cardiac surgery, according to a large international study led by McMaster University. Based on patients at 28 health centres in 13 countries, the results show less than one per cent of deaths of these patients occurred in the operating room, but 29 per cent of deaths occurred after discharge from hospital.
July 11, 2019
The 2019 Global Ranking of Academic Subjects has ranked McMaster’s clinical medicine and civil engineering programs 29th in the world. The clinical medicine is ranked second in Canada, and the civil engineering program is third in the country.
May 23, 2019
Deborah Cook, a renowned McMaster University professor, researcher and physician, has been named the recipient of the Canadian Institutes for Health Research (CIHR) Gold Leaf Prize for Impact.
March 14, 2019
McMaster University is receiving $8.45 million from the federal government to support 13 health research projects.
October 19, 2017 by Lori Dillon
The Good Bugs, Bad Bugs program, led by Canada Research Chair in Chemical Biology, Eric Brown, received nearly $6 million to allow researchers to generate a more thorough understanding of the ways in which microbes benefit us and sometimes cause disease.