The Division of Neurology is committed to providing the best neurology by supporting and advancing research. The division is very research-intensive, particularly in stroke and cognition. Research is incorporated and an important activity in our postgraduate and fellowship programs.
NAVIGATE ESUS was a global trial lead by our stroke group at PHRI that tested a factor Xa inhibitor in patients with embolic stroke of undetermined source.
COMPASS-MIND was an MRI imaging sub-study of the COMPASS trial that evaluated the incidence of clinically silent brain ischemia. AXIOMATIC-SSP is a global phase 2 randomized trial of a novel factor XIa inhibitor for the prevention of recurrent stroke in patients after stroke or TIA.
ENRICH-AF is evaluating the use of a DOAC in high-risk atrial fibrillation patients with previous intracranial hemorrhage.
McMaster initiated hemorrhagic stroke studies include NASPAF-ICH, CoHESIVE, and SATURN, among others. The stroke group collaborates on many national and international stroke studies.
The MS program contributes to the Canadian Multiple Sclerosis Working Group recommendations. We contribute and work with the Ontario Neurodegenerative Disease Research Initiative (ONDRI) in ALS and Dementia. The ALS program is involved in a number of therapeutic drug trials and continues basic research in understanding the biology of ALS. European collaborations are investigating the development of automated methods for EEG seizure detection and the utility of slow-wave activity in EEG in patients with low-grade glioma.
Neurology residents have been very successful in research projects that include, identifying the utility of echocardiography in patients with stroke, investigating the cognitive function of patients with COPD, testing perineural hydrodissection for patients with carpal tunnel syndrome, and the development of an acute ischemic stroke and hemorrhagic stroke registries.
Further details on ongoing and completed research projects on Stroke & Cognition can be accessed in the Population Health Research Institute website.
November 30, 2020
November 9, 2020
November 9, 2020
September 18, 2020
Five McMaster University professors, all members of the Faculty of Health Sciences, are joining the Canadian Academy of Health Sciences (CAHS) as fellows.
September 15, 2020
It has been a year since the release of the McMaster Textbook of Internal Medicine, and already, it’s been accessed by tens of thousands of people around the world.
September 10, 2020
August 11, 2020
Working together, researchers at McMaster University and the University of Waterloo are searching for how the SARS-CoV-2 virus infects the lungs – and they’re challenging what has become an accepted truth about the virus.
August 5, 2020
Much has been made recently about the new antiviral drug remdesivir for COVID-19 patients, but a McMaster University-led guideline for physicians warns that it would only be used in the most serious cases, and more research is needed.
August 4, 2020
Researchers at McMaster University and the Royal Ontario Museum (ROM) have reported the discovery and diagnosis of an aggressive malignant bone cancer — an osteosarcoma — for the first time ever in a dinosaur.
July 23, 2020
A new McMaster University-based network will bring together researchers and patients to tackle sepsis — a leading cause of death in COVID-19.
July 14, 2020
July 13, 2020
June 25, 2020
McMaster University has garnered $20 million in new funding for 17 COVID-19 research projects from the Canadian Institutes of Health Research (CIHR) and their funding partners.
May 25, 2020
The evidence shows that cloth masks, particularly those with several layers of cotton cloth, block droplet and aerosol contamination of the environment, may reduce transmission of COVID-19.
April 14, 2020
Health sciences and engineering researchers at McMaster University have been racing to assist Woodbridge Foam Corporation in getting a new made-in-Canada mask designed, tested and certified, as supplies of existing medical masks become less certain.