FIRH conducts research to increase understanding of respiratory health and disease through collaborative basic and clinical investigations with the expectation of improving patient care. Research is wide-ranging, from basic studies of animal models of lung disease (asthma, COPD, fibrosis) to clinical trials and epidemiological studies such as the Canadian Healthy Infant Longitudinal Development Study (CHILD) birth cohort study, for which the FIRH is hosting the coordinating center. Specialized facilities have been established at the FIRH, such as the Sputum Research Laboratory and the Aerosol Research Laboratory. Scientists at the FIRH are performing studies of bone marrow progenitor cells, airway peptide challenges, electrophysiological studies of airway smooth muscle cells, chronic allergen challenges, preclinical models of lung injury and repair, and more. The research productivity of FIRH is attested to by the high quality and impact of the peer-reviewed publications.