Extraneuronal manifestations in Spinal Muscular Atrophy - Dr. Rashmi Kothary - University of Ottawa

Schedule

Start 16 December, 2021, 12 PM

End 1 PM

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Location

Online

Online

Online

Online

Contact Info

Nora Roberge

E-Mail: modr@mcmaster.ca

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Dr. Kothary is the Deputy Scientific Director and Senior Scientist at the Ottawa Hospital Research Institute (OHRI). He received a Ph.D. in Biochemistry from the University of British Columbia and pursued postdoctoral research in the laboratories of Dr. Janet Rossant at the Mount Sinai Hospital Research Institute in Toronto and Dr. Azim Surani in Cambridge, U.K. It was during these formative years that Dr. Kothary developed his interests in pre-clinical models to study disease pathology. He has held the University Health Research Chair in Neuromuscular Disorders and is a Professor at the University of Ottawa. His current research focuses on investigating factors important for oligodendrocyte mediated myelination and remyelination of the CNS (in the context of Multiple Sclerosis) and understanding Spinal Muscular Atrophy pathogenesis to identify novel therapeutics for this devastating children’s disease. He currently sits on the SMA Beyond advisory board, has served on the scientific advisory board for CIHR IMHA, MDA and Cure SMA, and is a reviewer for the CIHR, NIH and Shriners Hospitals for Children.

LEARNING OBJECTIVES

  1. Gain an understanding of the genetics of spinal muscular atrophy (SMA)
  2. From bench to bedside – what are the current therapeutic options for SMA
  3. SMA is more than a motor neuron disease – do fatty liver and lipid abnormalities play a role in the disease?

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