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Dr. Alexandre Caron is an Assistant Professor in the Faculty of Pharmacy at Université Laval. Dr. Caron holds the Canada Research Chair in NeuroMetabolic Pharmacology. His research focuses on the pathophysiological mechanisms that alter brain-organs communication in metabolic diseases and aims to identify new molecular and pharmacological targets to improve energy and glucose metabolism.
After obtaining his PhD in Physiology-Endocrinology in 2015, Dr. Caron joined the laboratory of Dr. Joel Elmquist (Center for Hypothalamic Research, Department of Internal Medicine, University of Texas Southwestern Medical Center) first as a Diabetes Canada Postdoctoral Fellow and then as a Banting Postdoctoral Fellow. His postdoctoral work aimed at understanding how the central leptin-melanocortin system controls adipose metabolic and endocrine functions. During this time, he developed an arsenal of genetic models allowing the manipulation of key autonomic receptors. In 2019, Dr. Caron received the NIDDK K99/R00 Award to perform studies aimed at better understanding the sympathetic regulation of liver metabolism. Under the mentorship of Dr. Shawn Burgess (Center for Human Nutrition, University of Texas Southwestern Medical Center), he started combining mouse genetics, chemogenetics and stable isotope approaches to interrogate liver metabolism. In March 2020, he decided to come back home to establish his laboratory at the Quebec Heart and Lung Institute, where he is affiliated with the Montreal Diabetes Research Center.