Demystifying Medicine Video

Homeostatic regulation is critical for ensuring the functionality of the human body. Endocrine disrupting chemicals (EDCs) interfere with this process. Since there are many types of EDCs, compounds such as dioxins are indisputably associated with a myriad of health outcomes, while others are debated upon heavily, such as phytoestrogens. This video will discuss isoflavones, which are considered to be among the most estrogenic phytoestrogens, to answer the question of whether isoflavones are truly endocrine disruptors.

This video is provided for general and educational information only. Please consult your health care provider for Information about your health.

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Author Details


  • Bennetts, H. W.; Uuderwood, E. J.; Shier, F. L. A SPECIFIC BREEDING PROBLEM OF SHEEP ON SUBTERRANEAN CLOVER PASTURES IN WESTERN AUSTRALIA. Australian Vet J 1946, 22 (1), 2–12.
  • Casals-Casas, C.; Desvergne, B. Endocrine Disruptors: From Endocrine to Metabolic Disruption. Annual Review of Physiology 2011, 73 (1), 135–162.
  • Křížová, L.; Dadáková, K.; Kašparovská, J.; Kašparovský, T. Isoflavones. Molecules 2019, 24 (6), 1076.
  • Messina, M.; Mejia, S. B.; Cassidy, A.; Duncan, A.; Kurzer, M.; Nagato, C.; Ronis, M.; Rowland, I.; Sievenpiper, J.; Barnes, S. Neither Soyfoods nor Isoflavones Warrant Classification as Endocrine Disruptors: A Technical Review of the Observational and Clinical Data. Crit Rev Food Sci Nutr 2021, 1–57.
  • Patisaul, H. B.; Jefferson, W. The Pros and Cons of Phytoestrogens. Frontiers Neuroendocrinology 2010, 31 (4), 400–419. in VanPutte, C. L.; Seeley, R. R.; Regan, J. L.; Russo, A. F. Seeley’s Essentials of Anatomy & Physiology, Tenth.; 2019.

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