Demystifying Medicine Video



Have you ever thought about the effects Hepatitis C (HCV) may have on individuals? Did you ever think about whether or not the disease can be fatal? Be sure to watch this video to make sure you find out the molecular mechanisms of the disease, symptoms, and methods of transmission in place. This video will give you insight of statistics in Canada as well as globally on cure rate, survival rate, and death rates of HCV.

Kindly click the following link for the video transcript with timestamps: https://docs.google.com/document/d/12... dit?usp=sharing

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References
  • Canada, P. (2018, June 07). Government of Canada. Retrieved November 08, 2020, from https://www.canada.ca/en/public-healt... able-disease-report-ccdr/monthly-issue/2018-44/issue-7-8-july-5-2018/article-7-hepatitis- c-canada-2018-infographic.html
  • Canada, P. (2020, August 14). Government of Canada. Retrieved November 08, 2020, from https://www.canada.ca/en/public-healt...
  •  Commissioner, O. (n.d.). Hepatitis C Treatments Give Patients More Options. Retrieved November 08, 2020, from https://www.fda.gov/consumers/consume... more-options
  • Carrat, F., Fontaine, H., Dorival, C., Simony, M., Diallo, A., Hezode, C., ... & Zoulim, F. (2019). Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study. The Lancet, 393(10179), 1453-1464. doi: https://doi.org/10.1016/S0140-6736(18...
  • Gale, M., Blakely, C. M., Kwieciszewski, B., Tan, S. L., Dossett, M., Tang, N. M., ... & Katze, M. G. (1998). Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Molecular and cellular biology, 18( 9), 5208-5218. doi: 10.1128/MCB.18.9.5208
  • Ghany, M. G., Marks, K. M., Morgan, T. R., Wyles, D. L., Aronsohn, A. I., Bhattacharya, D., ... & Heller, T. (2019). Hepatitis C guidance 2019 update: AASLD-IDSA recommendations for testing, managing, and treating hepatitis C virus infection. Hepatology, 71(2), 686-721. doi: 10.1002/hep.31060
  • Hepatitis C Symptoms. Diagnosing Hepatitis C - ALF. (2020, March 10). Retrieved November 08, 2020, from https://liverfoundation.org/for-patie... gnosing-hepatitis-c/
  • Hepatitis C Treatment. Treatment for Hepatitis C Info - ALF. (2020, April 13). Retrieved November 08, 2020, from https://liverfoundation.org/for-patie... ting-hepatitis-c/
  • National Progress Report 2025 Goal: Reduce reported rate of hepatitis C-related deaths by ≥20%. (2020, August 11). Retrieved November 08, 2020, from https://www.cdc.gov/hepatitis/policy/...
  • Khatun, M., & Ray, R. B. (2019). Mechanisms underlying hepatitis C Virus-associated hepatic fibrosis. Cells, 8( 10), 1249. doi: https://doi.org/10.3390/cells8101249
  • Owens, D. K., Davidson, K. W., Krist, A. H., Barry, M. J., Cabana, M., Caughey, A. B., ... & Ogedegbe, G. (2020). Screening for hepatitis C virus infection in adolescents and adults: US Preventive Services Task Force recommendation statement. Jama, 323(10), 970-975. doi: 10.1001/jama.2020.1123
  • Schillie, S., Wester, C., Osborne, M., Wesolowski, L., & Ryerson, A. B. (2020). CDC recommendations for hepatitis C screening among adults—United States, 2020. MMWR Recommendations and Reports, 69( 2), 1. doi: 10.15585/mmwr.rr6902a1
  • van de Laar, T. J., van der Bij, A. K., Prins, M., Bruisten, S. M., Brinkman, K., Ruys, T. A., ... & Jurriaans, S. (2007). Increase in HCV incidence among men who have sex with men in Amsterdam most likely caused by sexual transmission. The Journal of infectious diseases, 196( 2), 230-238. doi: https://doi.org/10.1086/518796
  • Vescovo, T., Refolo, G., Vitagliano, G., Fimia, G. M., & Piacentini, M. (2016). Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma. Clinical Microbiology and Infection, 22( 10), 853-861. doi: https://doi.org/10.1016/j.cmi.2016.07...
  • Zeisel, M. B., Fofana, I., Fafi-Kremer, S., & Baumert, T. F. (2011). Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. Journal of hepatology, 54(3), 566-576. doi: https://doi.org/10.1016/j.jhep.2010.1...

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