Demystifying Medicine Video

Idiopathic pulmonary fibrosis (IPF) is a disorder characterized by chronic and progressive scarring of lung tissue. The cause of this disease is currently unknown. However, it can significantly impair one’s quality of life as patients often experience difficulty breathing. The seriousness of this disease makes finding effective treatment of paramount importance. Current pharmacological interventions are riddled with side-effects. Several clinical trials are underway in hopes of finding an effective therapy with little to no side-effects. One of the drugs showing promise as a potential therapeutic for IPF is GB0139 (formerly TD139). Here, we delve deeper into the mechanism by which GB0139 functions and its current status within clinical trials, providing hope for individuals who have been diagnosed with IPF.

GB0139 (formerly TD139) - Specific Articles:
Hamilton Pulmonary Fibrosis Support

Group Contact: Stephen Binch 289-456-7223
Meeting Location: Fortino's Community Room, 1579 Main St West Hamilton, ON L8S 1E6

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  • Rajput, V. K., MacKinnon, A., Mandal, S., Collins, P., Blanchard, H., Leffler, H., ... & Nilsson, U. J. (2016). A Selective Galactose–Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model. Journal of medicinal chemistry, 59(17), 8141-8147.
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