Demystifying Medicine Video



Vitamin B12 deficiency can occur in all kinds of individuals. It may be of particular concern if you are following a vegan or vegetarian diet, or taking medications that reduce your absorption ability of vitamins. This video looks at what exactly a vitamin B12 deficiency can lead to and the ways in which you can obtain vitamin B12 through your diet or by taking B12 supplements.

[Please complete our feedback form]




References
  • Bruins Slot, W., Merkus, F. W., Deventer, S. J. H. V. and Tytgat, G. N. (1997). Normalization of plasma vitamin B12 concentration by intranasal hydroxocobalamin in vitamin B12-deficient patients. Gastroenterology, 113, 430-433.
  • Daily Intake. (2017). Canadian Food Inspection Agency. Retrieved 30 October 2017.
  • Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline, pp. 306-356. Washington (DC): National Academies Press (US); 1998.
  • Ermens, A., Vlasveld, L. and Lindemans, J. (2003). Significance of elevated cobalamin (vitamin B12) levels in blood. Clinical Biochemistry,36(8), 585-590. doi:10.1016/j.clinbiochem.2003.08.004
  • Ganeson, S., Thanawala, N. and Hussain, N. (2013). Vitamin B12 deficiency: a treatable cause of developmental delay in infancy. J Paediatric Child Health, 49(4): E348-349. doi: 10.1111/jpc.12158
  • Gropper SS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism: Fourth Edition. Boston, MA: Wadsworth (2004).
  • Hashim, O. H. and Adnan, N. A. (1994). Coenzyme, cofactor and prosthetic group — Ambiguous biochemical jargon. Biochemical Education,22(2), 93-94. doi:10.1016/0307-4412(94)90088-4
  • Hvas, A. and Nexo, E. (2006). Diagnosis and treatment of vitamin B12 deficiency. An update. Haematologica, 91(11), 1506-1512.
  • Kwong, J. C., Carr, D., Dhalla, I. A., Tom-Kun, D. and Upshur, R. E. (2005). Oral vitamin B 12 therapy in the primary care setting: a qualitative and quantitative study of patient perspectives. BMC family practice, 6(1), 8.
  • Langan, R. C. and Goodbred, A. J. (2017). Vitamin B 12 Deficiency: Recognition and Management. American Family Physician, 96(6).
  • Miller, A., Korem, M., Almog, R. and Galboiz, Y. (2005). Vitamin B12, demyelination, remyelination and repair in multiple sclerosis. Journal of the Neurological Sciences,233(1-2), 93-97. doi:10.1016/j.jns.2005.03.009
  • Møllehave, L. T., Skaaby, T., Simonsen, K. S., Thuesen, B. H., Mortensen, E. L., Sandholt, C. H., ... and Linneberg, A. (2017). Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies. European Journal of Clinical Nutrition, 71(9), 1054-1060.
  • National Heart, Lung, and Blood Institute (2011). What are the signs and symptoms of pernicious anemia? Retrieved 30 October 2017.
  • Niculescu, M. and Zeisel, S. (2002). Diet, Methyl Donors and DNA Methylation: Interactions between Dietary Folate, Methionine and Choline. The Journal of Nutrition,132, 2333-2335.
  • Oh, R. and Brown, D. (2003). Vitamin B12 Deficiency. American Family Physician, 67(5), 979-986. Retrieved 30 October 2017.
  • Osimani, A., Berger, A., Friedman, J., Porat-Katz, B. S. and Abarbanel, J. M. (2005). Neuropsychology of vitamin B₁₂ deficiency in elderly dementia patients and control subjects. Journal of Geriatric Psychiatry and Neurology, 18(1), 33-38.
  • Vogiatzoglou, A., Smith, A. D., Nurk, E., Berstad, P., Drevon, C. A., Ueland, P. M., ... and Refsum, H. (2009). Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study. The American Journal of Clinical Nutrition, 89(4), 1078-1087.
  • Whitney, E., Rolfes, S., Hammond, G. and Piche, L. (2011). Understanding Nutrition (1st ed., pp. 332-334). Toronto: Nelson Education Ltd.